How much weight will I lose taking semaglutide?
Most people lose 10-15% of starting body weight over 3-6 months. For example, 200 pounds dropping to 170-180 pounds. Greater degrees of weight loss occur with larger starting weights. Diet and exercise boost results.
When will I notice appetite/weight changes from semaglutide?
Appetite reduction and weight loss effects begin within 2-4 weeks, become noticeable by 8 weeks, and peak by 3-6 months as dosage stabilizes. Gradual and steady losses are typical.
How long should I stay on semaglutide?
At least 12 months is recommended to solidly establish new weight setpoint and eating habits. Continuing 1-3 years provides optimization of body composition, blood sugars, and heart health.
Can semaglutide reverse type diabetes?
Yes, semaglutide has robust A1C lowering allowing many patients to achieve remission of diabetes. Diet quality and regular activity preserve these gains long-term. Many sustain drug-free diabetes remission for years.
What other medications work well with semaglutide?
Common pairings for additive weight loss include phentermine, metformin, SGLT2 inhibitors, GLP1/GIP dual agonists, and anti-obesity medications like Wegovy and Mounjaro.